Manjeet K Paintlia Selected Research

Lovastatin (Mevacor)

9/2013	Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-α-dependent mechanism.
11/2010	Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
1/2009	Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
12/2008	Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
9/2006	Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
9/2005	HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
10/2004	Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.

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Manjeet K Paintlia Research Topics

Disease

11	Demyelinating Diseases (Demyelinating Disease) 01/2015 - 10/2004
10	Multiple Sclerosis 09/2013 - 09/2005
7	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 08/2013 - 10/2004
4	Inflammation (Inflammations) 08/2013 - 09/2006
3	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2013 - 09/2012
3	Infections 10/2008 - 06/2002
2	Vitamin D Deficiency 01/2015 - 09/2012
2	Neuroinflammatory Diseases 04/2006 - 09/2005
2	Fibrosis (Cirrhosis) 10/2003 - 06/2002
1	Body Weight (Weight, Body) 01/2015
1	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2015
1	Neurologic Manifestations (Neurological Manifestations) 08/2013
1	Gliosis 02/2013
1	Autoimmune Diseases (Autoimmune Disease) 06/2009
1	Premature Obstetric Labor (Premature Labor) 10/2008
1	Fetal Death 10/2008
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 06/2002
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 06/2002

Drug/Important Bio-Agent (IBA)

7	Lovastatin (Mevacor)FDA LinkGeneric 09/2013 - 10/2004
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2010 - 10/2004
4	CytokinesIBA 09/2013 - 06/2002
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 09/2013 - 11/2010
2	Cholecalciferol (Vitamin D3)FDA Link 01/2015 - 09/2012
2	Metformin (Glucophage)FDA LinkGeneric 08/2013 - 06/2009
2	AMP-Activated Protein KinasesIBA 08/2013 - 09/2006
2	AntioxidantsIBA 02/2011 - 10/2008
2	RolipramIBA 01/2009 - 12/2008
2	PPAR alphaIBA 05/2008 - 04/2008
1	GalactosylceramidaseIBA 01/2015
1	Psychosine (Galactosylsphingosine)IBA 01/2015
1	Vitamin D FDA LinkGeneric 01/2015
1	VitaminsIBA 01/2015
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 09/2013
1	Ciliary Neurotrophic Factor (CNTF)IBA 02/2013
1	Calcitriol (Calcijex)FDA LinkGeneric 09/2012
1	Interleukin-17 (Interleukin 17)IBA 02/2011
1	Drug CombinationsIBA 01/2009
1	Oxidoreductases (Dehydrogenase)IBA 12/2008
1	Phospholipids (Phosphatides)FDA LinkGeneric 10/2008
1	Cysteine (L-Cysteine)FDA Link 10/2008
1	LipopolysaccharidesIBA 10/2008
1	PPAR gammaIBA 04/2006
1	Interleukin-4 (Interleukin 4)IBA 04/2006
1	NF-kappa B (NF-kB)IBA 04/2006
1	LipidsIBA 09/2005
1	Monoclonal AntibodiesIBA 10/2003
1	ChemokinesIBA 06/2002
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2002
1	Methylprednisolone FDA LinkGeneric 06/2002

Therapy/Procedure

6	Therapeutics 01/2015 - 09/2006
1	Induced Abortion (Induced Abortions) 10/2008